In a recent study published in the journal Nature Biotechnology, researchers describe the pA regulator system based on a ribonucleic acid (RNA)-based switch to regulate mammalian gene expression by ...

Northwestern Medicine scientists have developed a deep learning algorithm capable of identifying the location where a genetic process called polyadenylation occurs on the genome, according to findings ...

A new deep learning framework called PolyAnalysis estimates RNA poly(A) tail lengths directly from raw nanopore sequencing signals and profiles 3′-end regulation with confidence-aware analyses of p ...

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to ...

The ability to control the expression of therapeutic genes within a “therapeutic window” is crucial to ensure the development of safe and effective gene therapies, but to date, there has been no ...

COVID-19 accelerated efforts to develop faster, more efficient ways of manufacturing high-quality RNA sequences.